Gene Expression, Molecular Diagnosis & Modern Therapeutic Means

The Laboratory of Gene Expression, Molecular Diagnosis and Modern Therapeutic Methods of the Department of Molecular Biology and Genetics, of the Health Sciences Schools of the Democritus University of Thrace was established in 2002 with the aim of achieving excellence in the education of undergraduate and postgraduate students in the various fields of molecular biology and genetics and conducting high-level biomedical research. The field of Gene Expression, Molecular Diagnosis and Modern Therapeutic Methods has undergone exciting changes and rapid progress in recent years. This progress, combined with the rapid development of new technologies for genome research, is transforming Molecular Biology and its applications for the benefit of humanity.

Laboratory Details

Laboratory Title: Gene Expression, Molecular Diagnosis & Modern Therapeutic Means

Faculty: Faculty of Health Sciences

School: Molecular Biology and Genetics

Email: rms.lab.duth@gmail.com

Telephone: +30 25510 30623

Official Gazette of Establishment:

Introduction - Presentation

The Laboratory of Gene Expression, Molecular Diagnosis and Modern Therapeutic Methods of the Department of Molecular Biology and Genetics, of the Health Sciences Schools of the Democritus University of Thrace was established in 2002 with the aim of achieving excellence in the education of undergraduate and postgraduate students in the various fields of molecular biology and genetics and conducting high-level biomedical research. The field of Gene Expression, Molecular Diagnosis and Modern Therapeutic Methods has undergone exciting changes and rapid progress in recent years. This progress, combined with the rapid development of new technologies for genome research, is transforming Molecular Biology and its applications for the benefit of humanity.

Field of Research

The laboratory’s research activities focus on: 1. The study of gene expression from transcription to the secretion of biopolymers in extracellular vesicles, with the aim of discovering biomarkers and utilizing them as molecular diagnostic markers or therapeutic targets, 2. The application of recombinant DNA technology to produce synthetic polypeptides, 3. The study of cellular and molecular mechanisms, as well as mechanisms of response to endogenous or exogenous stress in physiological and pathological conditions of chronic stress, such as cancer, 4. In the study of the relationship between molecular structure and function, as well as in the isolation of natural proteins of high added value with important biotechnological applications, mainly in health and nutrition,  5. In the study of molecular and cellular mechanisms of action of microorganisms and their exploitation for the development of innovative applications in Molecular Diagnostics and Biotechnology.

Laboratory Members

Name Position/Capacity Email Telephone
Raphael Sandaltzopoulos Director rmsandal@mbg.duth.gr
Antonios Giannakakis Faculty Member antgian@mbg.duth.gr

Featured Research Programs

Programme Title Duration Funding
83726 - Non-Invasive Fish Monitoring Network for Reef Fishes in the Black Sea Basin (WatchReefFish) 2026-2028 National Resources
83070: APPLICATION OF eDNA TECHNOLOGY FOR MONITORING FISH STOCKS AND GENETIC RESOURCES IN THE AQUATIC ENVIRONMENT OF THE THRACIAN SEA AS A TOOL FOR SUSTAINABLE MANAGEMENT (ECOeDNA) 2023-2025 Green Fund/National Resources
82584 "USE OF OMICS TECHNOLOGIES FOR THE MOLECULAR CHARACTERIZATION AND ENRICHMENT OF BREAST MILK FOR NEWBORNS" 2020-2023 NSRF/ESPA 2014–2020

Featured Publications

Chronological Order APP doi
2026 Giannakakis https://doi.org/10.1093/nar/gkaf1174
2025 Sandaltzopoulos https://doi.org/10.3390/microorganisms13102373
2024 Giannakakis https://doi.org/10.3390/nu16142175

Infrastructure and Equipment

Patents

There are no featured patents.

Spin Offs

There are no registered SpinOffs