Biomolecular structure and biophysical analysis
The Laboratory of Biomolecular Structure and Biophysical Analysis was founded in 2015, and supports the educational and research work of the Department of Molecular Biology and Genetics in the fields of Structural Biology (determination of the 3D structure of proteins and nucleoprotein complexes using X-ray crystallography), Protein Biochemistry (overexpression and purification of biomolecules using chromatographic methods), Study and characterization of enzyme structure-function relationships, Structural Bioinformatics (structure-function analysis using computational methods), and Biophysics.The lab research focuses on studying the structure-function relationship of proteins, uncovering the atomic details that drive life’s processes and exploring how subtle changes—like a single mutation or a small displacement of a structural element—can dramatically alter protein function and contribute to health and disease.
